Oct 31, · Common signs and symptoms of ASD in adults can include: clumsiness. difficulty making conversation. difficulty making or maintaining close friendships. discomfort during eye contact. challenges with regulating emotions. extreme interest in one particular topic, such as a specific period of history. Author: Jayne Leonard. Aug 18, · Having overly focused interests, such as with moving objects or parts of objects. Getting upset by slight changes in a routine. Being more or less sensitive than other people to sensory input, such as light, noise, clothing, or temperature. People with ASD may also experience sleep problems .