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Oct 31,  · Common signs and symptoms of ASD in adults can include: clumsiness. difficulty making conversation. difficulty making or maintaining close friendships. discomfort during eye contact. challenges with regulating emotions. extreme interest in one particular topic, such as a specific period of history. Author: Jayne Leonard. Aug 18,  · Having overly focused interests, such as with moving objects or parts of objects. Getting upset by slight changes in a routine. Being more or less sensitive than other people to sensory input, such as light, noise, clothing, or temperature. People with ASD may also experience sleep problems .